#1Onur M Orun(VUMC: Vanderbilt University Medical Center)H-Index: 3
#2Myrick C. Shinall(VUMC: Vanderbilt University Medical Center)H-Index: 13
Last. Rameela Raman(VUMC: Vanderbilt University Medical Center)H-Index: 6
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BACKGROUND The impact of specialist palliative care intervention in patients undergoing surgery for cancer has not been studied extensively. The SCOPE randomized controlled trial will investigate the effect of specialist palliative care intervention in cancer patients undergoing surgery for selected abdominal malignancies. The study protocol of the SCOPE Trial was published in December 2019. METHODS AND DESIGN The SCOPE Trial is a single-center, single-blind, prospective, randomized controlled t...
OBJECTIVE: We aimed to test our hypothesis that traditional Japanese (Kampo) medicine, hochuekkito (Hochu-ekki-to: HET) has a preventive effect for the symptoms on COVID-19. TRIAL DESIGN: The study is designed as a multi-center, interventional, parallel-group, randomized (1:1 ratio), investigator sponsored, two-arm study. PARTICIPANTS: Six thousand participants will be recruited from healthy hospital workers in 7 Japanese University Hospitals. INCLUSION CRITERIA: 1. Age from 20 to 75 years old a...
Diabetic foot osteomyelitis (DFO) poses a major disease burden. It can generally be treated with long-term antibacterial therapy. International guidelines recommend to base antibacterial therapy choices on percutaneous bone biopsy culture, while in practice, therapy is frequently based on (less invasive) ulcer bed cultures. It is currently unknown if treatment outcomes of DFO differ depending on the chosen diagnostic strategy. The BeBoP trial is a multicentre; randomised controlled; physician-, ...
#1Gholamreza Askari(IUMS: Isfahan University of Medical Sciences)H-Index: 27
#2Babak Alikiaii(IUMS: Isfahan University of Medical Sciences)H-Index: 4
Last. Mohammad Bagherniya(IUMS: Isfahan University of Medical Sciences)H-Index: 11
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OBJECTIVES: This study aims to investigate the efficacy of curcumin-piperine co-supplementation on oxidative stress factors, clinical symptoms, and mortality rate in patients with coronavirus (COVID-19) admitted to the intensive care unit (ICU). TRIAL DESIGN: This study is a randomized, placebo-controlled, double-blind, parallel-arm clinical trial. PARTICIPANTS: The study participants will be recruited from patients admitted to the ICU of Al-Zahra hospital with a definitive diagnosis of COVID-19...
The authors are retracting this article as ethical approval has been withdrawn. The corresponding author, Christopher Schnelle, stated on behalf of all coauthors that they agree to this retraction.
Last. James M.N. Duffy(UCL: University College London)H-Index: 25
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BACKGROUND Randomised controlled trials (RCTs) evaluating ectopic pregnancy have reported many different outcomes, which are themselves often defined and measured in distinct ways. This level of variation results in an inability to compare results of individual RCTs. The development of a core outcome set to ensure outcomes important to key stakeholders are collected consistently will guide future research in ectopic pregnancy. STUDY AIM To develop and implement a core outcome set to guide future...
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