Original paper
NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons
Abstract
Activation of Agouti-Related Peptide (AgRP)-expressing neurons promotes feeding and insulin resistance. Here, we examine the contribution of neuropeptide Y (NPY)-dependent signaling to the diverse physiological consequences of activating AgRP neurons. NPY-deficient mice fail to rapidly increase food intake during the first hour of either chemo- or optogenetic activation of AgRP neurons, while the delayed increase in feeding is comparable between...
Paper Details
Title
NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons
Published Date
Jan 23, 2020
Journal
Volume
11
Issue
1
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History