Effect of apigenin on whole transcriptome profile of TNFα‑activated MDA‑MB‑468 triple negative breast cancer cells

The lack of hormone receptors in triple negative breast cancer (TNBC) is associated with the inefficacy of anti‑estrogen chemotherapies, leaving fewer options for patient treatment and higher mortality rates. Additionally, as with numerous types of inflammatory breast cancer, infiltration of tumor associated macrophages and other leukocyte sub‑populations within the tumor inevitably lead to aggressive, chemo‑resistant, metastatic and invasive...