Original paper
Impaired functional capacity of polarised neonatal macrophages
Abstract
Neonatal sepsis is accompanied by impaired apoptotic depletion of monocytes and macrophages (MΦ), aberrant cytokine production, impaired cell metabolism, and sustained inflammation. Macrophage-colony stimulating factor (M-CSF) triggers the differentiation from monocytes into MΦ (MΦ-0). Interleukin-10 (IL10) and Interferon-gamma (IFNy) further differentiate MΦ subpopulations, the anti-inflammatory MΦ-IL10 and the pro-inflammatory MΦ-IFNy subtype....
Paper Details
Title
Impaired functional capacity of polarised neonatal macrophages
Published Date
Jan 17, 2020
Journal
Volume
10
Issue
1
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Notes
History