Original paper
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes
Abstract
Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underlying risk remain largely unknown. These regions were explored by combining association analysis with in silico genomic feature annotations. We defined 205 independent risk-associated signals with the set of credible causal variants in each one. In parallel, we used a Bayesian approach (PAINTOR) that combines genetic...
Paper Details
Title
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes
Published Date
Jan 1, 2020
Journal
Volume
52
Issue
1
Pages
56 - 73
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Notes
History