Micronutrients, Metabolic Complications, and Inflammation in Ugandan Children With HIV.

Published on May 1, 2020in Journal of Pediatric Gastroenterology and Nutrition2.937
· DOI :10.1097/MPG.0000000000002630
Sahera Dirajlal-Fargo8
Estimated H-index: 8
,
Lingpeng Shan3
Estimated H-index: 3
(Case Western Reserve University)
+ 8 AuthorsGrace A. McComsey59
Estimated H-index: 59
Sources
Abstract
Selenium, zinc and chromium are essential micronutrients. Their alterations have been associated with HIV disease progression, metabolic complications and mortality.This is a cross-sectional study in children with perinatally acquired HIV (PHIV, n = 57), HIV exposed uninfected (HEU, n = 59) and HIV unexposed uninfected (HIV-, n = 56) children aged 2-10 years old, age and sex matched, enrolled in Uganda. PHIV were on stable antiretroviral therapy (ART) with undetectable viral load. We measured plasma concentrations of selenium, zinc and chromium as well as markers of systemic inflammation, monocyte activation, and gut integrity.Among PHIV children, 93% had viral load
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