Review paper

Diagnosis and management of toxicities of immune checkpoint inhibitors in hepatocellular carcinoma

Volume: 72, Issue: 2, Pages: 320 - 341
Published: Feb 1, 2020
Abstract
Immune checkpoint inhibitors (ICIs) have reshaped cancer therapy. ICIs enhance T cell activation through various mechanisms and may help reverse the exhausted phenotype of tumour-infiltrating lymphocytes. However, disrupting the key role that checkpoint molecules play in immune homeostasis may result in autoimmune complications. A broad range of immune-related adverse events (irAEs) involve almost every organ but mostly affect the skin,...
Paper Details
Title
Diagnosis and management of toxicities of immune checkpoint inhibitors in hepatocellular carcinoma
Published Date
Feb 1, 2020
Volume
72
Issue
2
Pages
320 - 341
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.