Engineering Secretory Amyloids for Remote and Highly Selective Destruction of Metastatic Foci

Volume: 32, Issue: 7
Published: Dec 27, 2019
Abstract
Functional amyloids produced in bacteria as nanoscale inclusion bodies are intriguing but poorly explored protein materials with wide therapeutic potential. Since they release functional polypeptides under physiological conditions, these materials can be potentially tailored as mimetic of secretory granules for slow systemic delivery of smart protein drugs. To explore this possibility, bacterial inclusion bodies formed by a self‐assembled,...
Paper Details
Title
Engineering Secretory Amyloids for Remote and Highly Selective Destruction of Metastatic Foci
Published Date
Dec 27, 2019
Volume
32
Issue
7
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