Engineering

Intracerebral hemorrhage

Biology

Surgery

Fishery

Psychiatry

Spontaneous intracerebral hemorrhage

Neurology

Mechanical engineering

Intraventricular hemorrhage

Genetics

Pediatrics

Stroke (engine)

Gestational age

Internal medicine

Medicine

Pneumonia

Subarachnoid hemorrhage

Logistic regression

Baseline (sea)

Pregnancy

Brain and Behavior

Background and Purpose Hemorrhagic stroke, particularly nontraumatic spontaneous intracerebral hemorrhage (SICH), is a cerebrovascular condition with unfavorable outcomes. The aims of the present study were to evaluate patients who suffered from SICH and investigate the early outcomes in a single‐center study. Methods During a study ‐period of 6 years (2008–2014), 613 consecutive patients (mean age, 72 ± 12.7 years; 51.1% female), who suffered from nontraumatic SICH and were treated at the Department of Neurology at the University Hospital of Schleswig‐Holstein, Campus Lübeck, Germany, were included and prospectively analyzed. Results During a mean hospitalization time of 12 days, 148 patients (24.1%) died, 47% of those within the first 2 days and 79% within the first week. The patients who died stayed at the hospital for a shorter time (3) than those who survived ( p &lt; .001). In the multivariate logistic regression, following parameters were found to be associated with the in‐hospital mortality: female sex (OR, 2.0; 95%‐CI, 1.2–3.4; p = .009), a NIHSS score&gt; 10 (OR, 10.5; 95%‐CI, 5.6–19.5; p &lt; .001), history of hypertension (OR, 0.35; 95%‐CI, 0.19–0.64; p = .001), previous oral anticoagulation (OR, 2; 95%‐CI, 1.0–3.8; p = .032), and intraventricular extension of hemorrhage (OR, 2.8; 95%‐CI, 1.7–4.7; p = .001). At discharge, 192 patients (41.2%) showed favorable outcomes (mRS ≤ 2) whereas the median mRS of patients who survived was 3 (IQR 2–4). The good functional outcome at discharge from the acute hospital was decreased by an age&gt; 70 years (OR, 0.56; 95%‐CI, 0.35–0.9; p = .017), NIHSS score&gt; 10 at admission (OR, 0.07; 95%‐CI, 0.04–0.13; p &lt; .001), and development of pneumonia during hospitalization (OR, 0.35; 95%‐CI, 0.2–0.6; p &lt; .001). Conclusion The present study showed that SICH is a serious disease causing high mortality and disability, particularly in the early period after event.

Nontraumatic spontaneous intracerebral hemorrhage: Baseline characteristics and early outcomes