Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation
Abstract
Malaria pathogenesis relies on sexual gametocyte forms of the malaria parasite to be transmitted between the infected human and the mosquito host but the molecular mechanisms controlling gametocytogenesis remains poorly understood. Here we provide a high-resolution transcriptome of Plasmodium falciparum as it commits to and develops through gametocytogenesis.The gametocyte-associated transcriptome is significantly different from that of the...
Paper Details
Title
Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation
Published Date
Dec 1, 2019
Journal
Volume
20
Issue
1
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