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The biochemical basis of microRNA targeting efficacy
Abstract
Biochemical prediction of miRNA targeting MicroRNAs (miRNAs) regulate most human messenger RNAs and play essential roles in diverse developmental and physiological processes. Correctly predicting the function of each miRNA requires a better understanding of miRNA targeting efficacy. McGeary et al. measured binding affinities between six miRNAs and synthetic targets, built a biochemical model of miRNA-mediated repression, and expanded it to all...
Paper Details
Title
The biochemical basis of microRNA targeting efficacy
Published Date
Dec 20, 2019
Journal
Volume
366
Issue
6472
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