Original paper
Alzheimer’s disease-associated (hydroxy)methylomic changes in the brain and blood
Abstract
Late-onset Alzheimer's disease (AD) is a complex multifactorial affliction, the pathogenesis of which is thought to involve gene-environment interactions that might be captured in the epigenome. The present study investigated epigenome-wide patterns of DNA methylation (5-methylcytosine, 5mC) and hydroxymethylation (5-hydroxymethylcytosine, 5hmC), as well as the abundance of unmodified cytosine (UC), in relation to AD.We identified epigenetic...
Paper Details
Title
Alzheimer’s disease-associated (hydroxy)methylomic changes in the brain and blood
Published Date
Nov 27, 2019
Journal
Volume
11
Issue
1
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Notes
History