Original paper

Clinical efficacy and safety of dotinurad, a novel selective urate reabsorption inhibitor, in Japanese hyperuricemic patients with or without gout: an exploratory, randomized, multicenter, double-blind, placebo-controlled, parallel-group early phase 2 study

Volume: 24, Issue: S1, Pages: 44 - 52
Published: Nov 21, 2019
Abstract
Dotinurad, a novel selective urate reabsorption inhibitor (SURI) that has a future potential for the treatment of hyperuricemia, reduces serum uric acid levels by selectively inhibiting urate transporter 1 (URAT1). We evaluated the efficacy and safety of dotinurad in hyperuricemic Japanese patients with or without gout.The study design was an exploratory, early phase 2 study that ran for 8 weeks. It was a randomized, multicenter, double-blind,...
Paper Details
Title
Clinical efficacy and safety of dotinurad, a novel selective urate reabsorption inhibitor, in Japanese hyperuricemic patients with or without gout: an exploratory, randomized, multicenter, double-blind, placebo-controlled, parallel-group early phase 2 study
Published Date
Nov 21, 2019
Volume
24
Issue
S1
Pages
44 - 52
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