<p>Icariin Alleviates IL-1β-Induced Matrix Degradation By Activating The Nrf2/ARE Pathway In Human Chondrocytes</p>
Abstract
Osteoarthritis (OA) is characterized by progressive matrix destruction of articular cartilage. This study aimed to investigate the potential antioxidative and chondroprotective effects and underlying mechanism of Icariin (ICA) in interleukin-1 beta (IL-1β)-induced extracellular matrix (ECM) degradation of OA cartilage.Human chondrocyte cell line HC-A was treated with different doses of ICA, and then MTT assay and PI staining were used to...
Paper Details
Title
<p>Icariin Alleviates IL-1β-Induced Matrix Degradation By Activating The Nrf2/ARE Pathway In Human Chondrocytes</p>
Published Date
Nov 1, 2019
Volume
Volume 13
Pages
3949 - 3961
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