Molecularly Imprinted Polymers for Cell Recognition

Published on Apr 1, 2020in Trends in Biotechnology14.343
· DOI :10.1016/J.TIBTECH.2019.10.002
Stanislav S. Piletsky5
Estimated H-index: 5
(Imperial College London),
Francesco Canfarotta16
Estimated H-index: 16
+ 2 AuthorsSergey A. Piletsky77
Estimated H-index: 77
(University of Leicester)
Sources
Abstract
Since their conception 50 years ago, molecularly imprinted polymers (MIPs) have seen extensive development both in terms of synthetic routes and applications. Cells are perhaps the most challenging target for molecular imprinting. Although early work was based almost entirely around microprinting methods, recent developments have shifted towards epitope imprinting to generate MIP nanoparticles (NPs). Simultaneously, the development of techniques such as solid phase MIP synthesis has solved many historic issues of MIP production. This review briefly describes various approaches used in cell imprinting with a focus on applications of the created materials in imaging, drug delivery, diagnostics, and tissue engineering.
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