P3-345: BRAIN STRUCTURAL NETWORK EFFICIENCY IS ASSOCIATED WITH A HIERARCHY OF GRAY MATTER REGIONS: RESULTS FROM THE FRAMINGHAM HEART STUDY

Structural networks in the brain consist of gray matter (GM) regions as nodes and connecting white matter (WM) tracts as edges. Nodal efficiency is the efficiency of information propagation between a given node and all other nodes in the network, and is proportional to the inverse of the shortest path length at that node. Global efficiency (GE) is defined as the average nodal efficiency of the network, reflecting the integration of each node...