Impaired Cerebral Autoregulation in Alzheimer’s Disease: A Transcranial Doppler Study

Vasculature changes have been observed in Alzheimer's disease (AD). AD-related vascular pathology might impair cerebral autoregulation (CA).This study was designed to evaluate CA of AD patients by using transcranial doppler (TCD).A total of 61 participants were included in the study, including 31 AD patients and 30 controls. The trend curves of cerebral blood flow velocities (CBFV), pulsatility index, and resistance index were obtained using TCD...