Machine Learning to Predict Toxicity in Head and Neck Cancer Patients Treated with Definitive Chemoradiation

Concurrent chemoradiation (CRT) is one of the standard-of-care curative treatments for patients with head and neck cancer, but is associated with substantial morbidity. Proton radiation therapy (RT) may allow for decreased toxicity due to treatment related side-effects, but prospective studies are limited. We set out to use a machine learning (ML) approach to determine factors associated with morbidity in patients treated with CRT for head and...