Hallucinogen

Natural (archaeology)

Stereochemistry

Biology

Psychiatry

Paleontology

Chemistry

Schizophrenia (object-oriented programming)

Natural product

Antidepressant

Psychotropic drug

Drug

Antipsychotic

Anxiety

Medicine

Pharmacology

The International Journal of Neuropsychopharmacology

Multiple initiatives at the national and international level support natural drug discovery. Psychiatrists and patients are not well informed about natural psychotropics in general. Existing antidepressant and antipsychotic drugs were developed from atropine, a natural product. Subsequent drug developments were largely based on extension and modification of earlier molecular scaffolds. This limits their mechanisms of action to similar neuropathways. Natural psychotropic substances, particularly those with hallucinogenic and psychedelic properties and different chemical structures, may serve as new paths to novel psychotropic drug development.

Opportunities in Novel Psychotropic Drug Design from Natural Compounds