Choosing male or female

Reproductive Biology Mammals show dimorphic development with different germ cells and reproductive systems. Mullerian inhibiting substance (MIS) is key to mammalian dimorphic development. In males, the testis secretes MIS, which causes the regression of Mullerian ducts (which are the developmental rudiments for Fallopian tubes, uterus, cervix, and vagina). Using single-cell RNA sequencing, Saatcioglu et al. investigated the persistence of a...