siRNA- and miRNA-based therapeutics for liver fibrosis

Volume: 214, Pages: 17 - 29
Published: Dec 1, 2019
Abstract
Liver fibrosis is a wound-healing process induced by chronic liver injuries, such as nonalcoholic steatohepatitis, hepatitis, alcohol abuse, and metal poisoning. The accumulation of excessive extracellular matrix (ECM) in the liver is a key characteristic of liver fibrosis. Activated hepatic stellate cells (HSCs) are the major producers of ECM and therefore play irreplaceably important roles during the progression of liver fibrosis. Liver...
Paper Details
Title
siRNA- and miRNA-based therapeutics for liver fibrosis
Published Date
Dec 1, 2019
Volume
214
Pages
17 - 29
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