Original paper
An 89Zr-HDL PET Tracer Monitors Response to a CSF1R Inhibitor
Abstract
The immune function within the tumor microenvironment has become a prominent therapeutic target, with tumor-associated macrophages (TAMs) playing a critical role in immune suppression. We propose an 89Zr-labeled high-density lipoprotein (89Zr-HDL) nanotracer as a means of monitoring response to immunotherapy. Methods: Female MMTV-PyMT mice were treated with pexidartinib, a colony-stimulating factor 1 receptor (CSF1R)...
Paper Details
Title
An 89Zr-HDL PET Tracer Monitors Response to a CSF1R Inhibitor
Published Date
Aug 16, 2019
Journal
Volume
61
Issue
3
Pages
433 - 436
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Notes
History