Original paper
Modelling retention and peak shape of small polar solutes analysed by nano-HPLC using methacrylate-based monolithic columns
Abstract
The development of methacrylate-based monolithic columns was studied for the separation of pharmaceutical hydrophilic compounds in nano-liquid chromatography. The selected polymerisation mixture consisted of 7.5% hexyl methacrylate, 4.5% methacrylic acid and 18.0% ethylene dimethacrylate (w/w), in a binary porogenic solvent (35:35 w/w 1-propanol/1,4-butanediol). The polymer synthesised with this mixture has a good permeability, not excessive...
Paper Details
Title
Modelling retention and peak shape of small polar solutes analysed by nano-HPLC using methacrylate-based monolithic columns
Published Date
Dec 1, 2019
Journal
Volume
1086
Pages
142 - 155
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Notes
History