SOX17 in cellular reprogramming and cancer

Volume: 67, Pages: 65 - 73
Published: Dec 1, 2020
Abstract
SOX17 is a transcription factor directing the specification and development of the primitive endoderm, primitive germ cells, definitive endoderm and, subsequently, is involved in the cardiovascular system and several endoderm-derived organs. The analysis of cancer genome sequencing data classified SOX17 as mutated cancer driver gene in endometrial cancer. These studies identified hotspot missense mutations within its DNA binding and...
Paper Details
Title
SOX17 in cellular reprogramming and cancer
Published Date
Dec 1, 2020
Volume
67
Pages
65 - 73
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