Work‐up in the case of granulocyte antibodies

Granulocyte allo‐ and autoantibodies have been implicated in a variety of clinical conditions such as primary and secondary autoimmune neutropenia ( AIN ), alloimmune neutropenia ( NAIN ), transfusion‐related acute lung injury ( TRALI ) as well as febrile and severe pulmonary transfusion reactions. The classic granulocyte agglutination test ( GAT ) in combination with the granulocyte indirect immunofluorescence test ( GIFT ) can detect nearly...