Aldosterone in Gynecology and Its Involvement on the Risk of Hypertension in Pregnancy

Aldosterone is the main mineralocorticoid hormone, responsible of the regulation of fluid and electrolyte balance and blood pressure. It acts also as a pro-inflammatory factor responsible of an increased cardiovascular risk, independent from blood pressure values. After the discovery of mineralocorticoid receptor (MR) in mononuclear leukocytes, further studies support its role in inflammatory and even autoimmune mechanisms underlying several...