Bacterial Metabolism and Antibiotic Efficacy
Abstract
Antibiotics target energy-consuming processes. As such, perturbations to bacterial metabolic homeostasis are significant consequences of treatment. Here, we describe three postulates that collectively define antibiotic efficacy in the context of bacterial metabolism: (1) antibiotics alter the metabolic state of bacteria, which contributes to the resulting death or stasis; (2) the metabolic state of bacteria influences their susceptibility to...
Paper Details
Title
Bacterial Metabolism and Antibiotic Efficacy
Published Date
Aug 1, 2019
Journal
Volume
30
Issue
2
Pages
251 - 259
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