C-N cross-coupling reaction catalysed by efficient and reusable CuO/SiO₂ nanoparticles under ligand-free conditions

Nanometric copper oxide supported on silica has been found to be a highly efficient and reusable catalyst for the C–N cross‐coupling reaction of amines with aryl halides under ligand‐free conditions. Various arylamines with different substituted groups can be synthesized in moderate to good yields. The catalyst can be recycled at least five times without obvious loss in catalytic activity. Copyright © 2014 John Wiley & Sons,...