AB0668 ASSOCIATION OF ANTI-RNA POLYMERASE III ANTIBODY AND BREAST IMPLANTS RUPTURE IN ITALIAN PATIENTS WITH SYSTEMIC SCLEROSIS

Background:

Several epidemiological studies have investigated the link between silicone breast implants (SBI) and Systemic Sclerosis (SSc). Although discordant data were reported, a recent analysis of SBI followed by United States Food and Drug administration post approval studies, including nearly 100,000 individuals, described an association of SBI with a higher rate of SSc (Standardized incidence ratio 7.00), compared with normative...