One-step reductive amidation of nitro arenes: application in the synthesis of Acetaminophen™
Abstract
A novel thioacetate mediated one-step reductive acetamidation of aryl nitro compounds was developed and applied to an efficient synthesis of acetaminophen. The reaction also proceeds well without a solvent in the presence of a catalytic amount of...
Paper Details
Title
One-step reductive amidation of nitro arenes: application in the synthesis of Acetaminophen™
Published Date
Mar 1, 2006
Journal
Volume
47
Issue
11
Pages
1861 - 1864
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Notes
History