Original paper

Gene activation precedes DNA demethylation in response to infection in human dendritic cells

Volume: 116, Issue: 14, Pages: 6938 - 6943
Published: Mar 18, 2019
Abstract
DNA methylation is considered to be a relatively stable epigenetic mark. However, a growing body of evidence indicates that DNA methylation levels can change rapidly; for example, in innate immune cells facing an infectious agent. Nevertheless, the causal relationship between changes in DNA methylation and gene expression during infection remains to be elucidated. Here, we generated time-course data on DNA methylation, gene expression, and...
Paper Details
Title
Gene activation precedes DNA demethylation in response to infection in human dendritic cells
Published Date
Mar 18, 2019
Volume
116
Issue
14
Pages
6938 - 6943
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