Original paper
A molecular signature for anastasis, recovery from the brink of apoptotic cell death
Abstract
During apoptosis, executioner caspase activity has been considered a point of no return. However, recent studies show that cells can survive caspase activation following transient apoptotic stimuli, a process called anastasis. To identify a molecular signature, we performed whole-transcriptome RNA sequencing of untreated, apoptotic, and recovering HeLa cells. We found that anastasis is an active, two-stage program. During the early stage, cells...
Paper Details
Title
A molecular signature for anastasis, recovery from the brink of apoptotic cell death
Published Date
Aug 2, 2017
Journal
Volume
216
Issue
10
Pages
3355 - 3368
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Notes
History