OP0167 B LYMPHOCYTES DIRECTLY CONTRIBUTE TO TISSUE FIBROSIS IN IGG4-RELATED DISEASE

Published: Jun 1, 2019
Abstract

Background

IgG4-related disease (IgG4-RD) is a fibro-inflammatory condition marked by rapid clinical improvement after selective depletion of B lymphocytes with rituximab. This feature suggests that B cells might participate in fibrogenesis and wound healing (1-3).

Objectives

In the present work we aimed to demonstrate that B lymphocytes contribute directly to tissue fibrosis in IgG4-RD.

Methods

Total circulating CD19+...
Paper Details
Title
OP0167 B LYMPHOCYTES DIRECTLY CONTRIBUTE TO TISSUE FIBROSIS IN IGG4-RELATED DISEASE
Published Date
Jun 1, 2019
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