Added value of MRI tractography of peri-prostatic nerve plexus to conventional T2-WI in detection of extra-capsular extension of prostatic cancer

Published on Jun 13, 2019in Radiologia Medica2
· DOI :10.1007/S11547-019-01047-3
Adam Jerzy Cybulski5
Estimated H-index: 5
,
Matteo Catania5
Estimated H-index: 5
+ 4 AuthorsGiancarlo Mansueto22
Estimated H-index: 22
Sources
Abstract
Purpose To evaluate the role of DTI (with fibretracking) and T2-weighted imaging (T2-WI) used together for predicting extra-capsular extension in patients with localized prostate cancer.
📖 Papers frequently viewed together
12 Citations
42 Citations
References13
Newest
#1Valerio Di Paola (UCSC: Catholic University of the Sacred Heart)H-Index: 1
#2Adam Jerzy Cybulski (University of Verona)H-Index: 5
Last. Roberto Pozzi Mucelli (University of Verona)H-Index: 38
view all 6 authors...
Objective:To evaluate if diffusion tensor imaging (DTI) is able to detect changes of periprostatic neurovascular fibers (PNFs) before and after radical prostatectomy (RP), and if these changes are related to post-surgical urinary incontinence and erectile dysfunction.Methods:22 patients (mean age 62.6 years) with biopsy-proven prostate cancer underwent 1.5 T DTI before and after RP. The number, fractional anisotropy (FA) values and length of PNFs before and after RP were compared using Student’s...
7 CitationsSource
#1Sungmin Woo (SNU: Seoul National University)H-Index: 26
#2Jeong Y.eon ChoH-Index: 1
Last. Seung Hoon KimH-Index: 30
view all 4 authors...
OBJECTIVE. The objective of our study was to evaluate diffusion-weighted imaging (DWI) and T2-weighted imaging for predicting extracapsular extension (ECE) in patients with prostate cancer. MATERIALS AND METHODS. One hundred seventeen patients underwent preoperative 3-T MRI and radical prostatectomy. Two radiologists evaluated ECE with T2-weighted imaging based on the Prostate Imaging Reporting and Data System (PI-RADS). Then, the apparent diffusion coefficient (ADC) of the tumor calculated from...
42 CitationsSource
#1Valeria Panebianco (Sapienza University of Rome)H-Index: 32
#2Flavio Barchetti (Sapienza University of Rome)H-Index: 15
Last. Carlo Catalano (Sapienza University of Rome)H-Index: 71
view all 10 authors...
Abstract Objectives To evaluate if Diffusion Tensor Imaging technique (DTI) can improve the visualization of periprostatic nerve fibers describing the location and distribution of entire neurovascular plexus around the prostate in patients who are candidates for prostatectomy. Materials and methods Magnetic Resonance Imaging (MRI), including a 2D T2-weighted FSE sequence in 3 planes, 3D T2-weighted and DTI using 16 gradient directions and b = 0 and 1000, was performed on 36 patients. Three out o...
30 CitationsSource
#1David S. Finley (KP: Kaiser Permanente)H-Index: 27
#2Benjamin M. Ellingson (UCLA: University of California, Los Angeles)H-Index: 52
Last. Daniel Margolis (UCLA: University of California, Los Angeles)H-Index: 40
view all 8 authors...
Objective To evaluate the feasibility of diffusion tensor imaging (DTI) tractography of the prostate for mapping of periprostatic neurovascular anatomy. Methods Eight men with prostate cancer scheduled to undergo nerve-sparing robot-assisted radical prostatectomy (RARP) underwent endorectal multiparametric magnetic resonance imaging (MRI) of the prostate with DTI. Tract mapping was accomplished by positioning spherical regions of interest contiguously along the prostatic capsule at the prostatic...
29 CitationsSource
#1Guillaume PloussardH-Index: 33
#2Mohammad Ali AgamyH-Index: 1
Last. Laurent SalomonH-Index: 89
view all 10 authors...
Study Type – Therapy (case series) Level of Evidence 4 What’s known on the subject? and What does the study add? Despite excellent surgical cancer control, up to 40% of patients will have biochemical recurrence following radical prostatectomy (RP) for localized prostate cancer. Positive surgical margins (PSM) have been clearly demonstrated to be one of the main predictive factors for biochemical failure, disease progression and cancer mortality. However, decision of further management (adjuvant ...
69 CitationsSource
#1Guilherme Godoy (NYU: New York University)H-Index: 29
#2Basir Tareen (NYU: New York University)H-Index: 10
Last. Herbert Lepor (NYU: New York University)H-Index: 82
view all 3 authors...
to identify preoperative predictors of PSMs and BCR. The estimated 5-year risk of BCR was calculated using the Kaplan‐Meier method.
57 CitationsSource
#1John R. Srigley (U of T: University of Toronto)H-Index: 53
#2Peter A. Humphrey (WashU: Washington University in St. Louis)H-Index: 88
Last. Thomas M. Wheeler (BCM: Baylor College of Medicine)H-Index: 121
view all 12 authors...
193 CitationsSource
BACKGROUND AND PURPOSE: In progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD), postmortem studies show different topographic involvement of the thalamus, basal ganglia, and their cortical connections. Diffusion tensor imaging (DTI) is an MR imaging technique sensitive to gray and white matter microstructure integrity. This study was performed to determine whether DTI may demonstrate microstructural differences between PSP and CBD, particularly within the thalamus and its co...
83 CitationsSource
#1Jonathan A.D. Farrell (ICSCI: Kennedy Krieger Institute)H-Index: 16
#2Bennett A. Landman (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 41
Last. Susumu MoriH-Index: 106
view all 7 authors...
Purpose To develop an experimental protocol to calculate the precision and accuracy of fractional anisotropy (FA), mean diffusivity (MD), and the orientation of the principal eigenvector (PEV) as a function of the signal to noise ratio (SNR) in vivo.
292 CitationsSource
#1Anna Bill-Axelson (KI: Karolinska Institutet)H-Index: 27
#2Lars HolmbergH-Index: 103
Last. Jan-Erik JohanssonH-Index: 60
view all 15 authors...
BACKGROUND: In 2008, we reported that radical prostatectomy, as compared with watchful waiting, reduces the rate of death from prostate cancer. After an additional 3 years of follow-up, we now repo ...
1,722 CitationsSource
Cited By6
Newest
#1Anna Colarieti (UniSR: Vita-Salute San Raffaele University)H-Index: 3
#2Nikesh Thiruchelvam (University of Cambridge)H-Index: 9
Last. Tristan Barrett (University of Cambridge)H-Index: 36
view all 3 authors...
Prostate cancer is the second most common male cancer, and radical prostatectomy is a highly effective treatment for intermediate and high-risk disease. However, post-prostatectomy urinary incontinence remains a major functional side-effect in patients undergoing radical prostatectomy. Despite recent improvements in preoperative imaging quality and surgical techniques, it remains challenging to predict or prevent occurrence of this complication. The aim of this research was to review the current...
1 CitationsSource
#1Valerio Di PaolaH-Index: 3
#2Angelo TotaroH-Index: 12
Last. Riccardo Manfredi (UCSC: Catholic University of the Sacred Heart)H-Index: 51
view all 12 authors...
PURPOSE The knowledge of periprostatic nerve fiber (pNF) is still incomplete by means of conventional MRI. The purpose of our study was to demonstrate if DTI imaging is able to depict anatomical features of pNF. METHODS For this retrospective study, fifty-six patients (mean age 63.5 years), who underwent 1.5-T prostate MRI, including 32 directions DTI, were enrolled between October 2014 and December 2018. ANOVA test and Student's t-test were performed between the mean values of the number, FA va...
Source
#2Stefano Fanti (UNIBO: University of Bologna)H-Index: 83
Last. James A. Eastham (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 107
view all 9 authors...
Abstract Context Management of newly diagnosed prostate cancer (PCa) is guided in part by accurate clinical staging. The role of imaging, including magnetic resonance imaging (MRI) and positron emission tomography/computed tomography (PET/CT), in initial staging remains controversial. Objective To systematically review the studies of MRI and/or PET/CT in the staging of newly diagnosed PCa with respect to tumor (T), nodal (N), and metastatic (M) staging (TNM staging). Evidence acquisition We perf...
5 CitationsSource
Purpose: To assess whether the three-dimensional reconstructions of preoperative computed tomography (CT) scans are helpful for establishing extranodal extension (ENE) in head and neck carcinoma. Approach: Patients with a histological diagnosis of ENE (pENE + ) were considered “cases” and patients with negative histological examination for ENE (pENE − ) were considered “controls.” Cases and controls were divided into two groups: a major nodes (MaN) group (lymph nodes on CT > 15 mm) and a minor n...
1 CitationsSource
#1Francesco ZiglioliH-Index: 7
#2Umberto MaestroniH-Index: 13
Last. Massimo De FilippoH-Index: 13
view all 8 authors...
The growing interest in multiparametric MRI is leading to important changes in the diagnostic process of prostate cancer. MRI-targeted biopsy is likely to become a standard for the diagnosis of prostate cancer in the next years. Despite it is well known that MRI has no role as a staging technique, it is clear that multiparametric MRI may be of help in active surveillance protocols. Noteworthy, MRI in active surveillance is not recommended, but a proper understanding of its potential may be of he...
Source
#1Pierpaolo PalumboH-Index: 9
#2Rosa ManettaH-Index: 4
Last. Antonio BarileH-Index: 30
view all 10 authors...
Prostate cancer is the most common malignancy in male population. Over the last few years, magnetic resonance imaging (MRI) has proved to be a robust clinical tool for identification and staging of clinically significant prostate cancer. Though suggestions by the European Society of Urogenital Radiology to use complete multiparametric (mp) T2-weighted/diffusion weighted imaging (DWI)/dynamic contrast enhancement (DCE) acquisition for all prostate MRI examinations, the real advantage of functiona...
Source