Phenotype

Danish

Population

Biology

Gene

Endoplasmic reticulum

Philosophy

JAK2 V617F

Linguistics

Mutation

Calreticulin

Genetics

Medicine

Environmental health

Blood

CALR mutations are prevalent in the general population but are much less frequent compared with the estimated JAK2 V617F prevalence. JAK2 V617F and CALR mutations in the general population are linked to a distinct blood count profile, also in the absence of MPN diagnosis.

Prevalence and phenotypes of JAK2 V617F and calreticulin mutations in a Danish general population