A highly efficient memantine-modified palladium catalyst for Suzuki–Miyaura cross-coupling reaction

A new simple Pd(memantine)2Cl2 complex was synthesized and characterized by 1H NMR, 13C NMR and X-ray single crystal structure determination. The Suzuki–Miyaura reaction of aryl bromides catalyzed by Pd(memantine)2Cl2 complex was investigated in air with different temperature. The high turnover numbers of 650,000 have been obtained in the reaction of 4-bromonitrobenzene with phenylboronic acid at 80 °C. At room temperature, the complex also...