Last. Chen-Guo Feng(SHU: Shanghai University)H-Index: 6
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ABSTRACT An efficient synthesis of (+)-scrodentoid A was accomplished starting from commercially available dehydroabietic acid. Key reactions in the synthesis include oxidative decarboxylation of dehydroabietic acid and C-H bond oxidation on arene.
ABSTRACT Fluorescent nanoaggregates comprised of rhodamine based amphiphilic probe has been designed, which can simultaneously detect Al3+, Cr3+ and F¯ ions in the aqueous medium (pH 7.4). Mechanistic investigation indicates that both the carbonyl oxygen of the spirolactam ring and the nitrogen center of indole participate in the coordination of metal ions. Consequently, metal ion-binding induces the opening of the spirolactam ring and allows the Forster energy transfer from indole to xanthene m...
Abstract One-pot C-H azidation/azide-alkyne cycloaddition of 8-aminoquinoline at C-5 position is achieved with Nano-CuO. Variety of different substrates have been found compatible and gave the corresponding products from moderate to good yields. This strategy provides a practical method for the synthesis of triazole-substituted 8-aminoquinolines with one-pot, Nano-CuO-catalyst, mild reaction conditions and high step economy.
Last. Vittorio Pace(UNITO: University of Turin)H-Index: 28
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Abstract α-Fluoromethyl selenoethers were prepared through a sequential one-pot diselenide reduction-fluoromethylation with the fluorinated, highly manipulable C1 source ICH2F. The reaction benefited from the employment of the environmentally friendly solvent MeTHF (2-methyltetrahydrofuran) which enabled to maximize the efficiency of both steps of the technique. A series of variously functionalized analogues – featuring a remarkable degree of stability imparted by selenium - could be chemoselect...
Last. Zhiqiang Weng(FZU: Fuzhou University)H-Index: 23
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ABSTRACT A method for the synthesis of polysubstituted 4-difluoromethyl and perfluoroalkyl pyrazole derivatives by the Lewis acid- and base-co-mediated reaction of perfluoroacetyl diazoester with ketones is reported. A series of structurally diverse 4-difluoromethylated and perfluoroalkylated pyrazoles were obtained in moderate to good yields. The reactions proceeded smoothly under mild conditions with wide functional group tolerance.
Abstract Nowadays large quantities of volatile organic compounds (VOCs) are used, although they present serious disadvantages. Developing alternative reaction media capable of replacing VOCs is of the upmost relevance. Among the surrogates, deep eutectic solvents (DESs) have received particular attention. This revision gathers all the organocatalytic transformations carried out in DESs, benchmarking these protocols against the corresponding transformation operating in traditional VOC solvents.
ABSTRACT Сhemosensors based on 1H-indole, 1H-benzo[e]indole, and 1H-benzo[g]indole were synthesized. According to 1H, 13C NMR, X-ray diffraction study and DFT calculations, they exist predominantly in keto form, which absorbs at 371-404 nm and exhibit a low-intensity fluorescence at 454-527 nm. Recognition of Hg2+ cations in acetonitrile results in a bathochromic shift of the long-wave absorption band by ∼20 nm, accompanied by a “naked-eye” effect that causes the colorless solution to turn brigh...
Last. Ramesh Chandra(DU: University of Delhi)H-Index: 44
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Abstract We envisioned a facile construction of diversified pyrazinoindoles by using 1,1,1,3,3,3-Hexafluoroisopropanol (HFIP) as the solvent and catalyst, hence eliminating metal catalyzed routes for its development. The process is facilitated by HFIP that has emerged as a powerful tool for development of novel fused heterocycles. This cascade approach blends the asymmetric N-acylation with consecutive intramolecular cyclisation via Pictet-Spengler reaction as an efficient tool forming overall t...