Review paper
FGF19–FGFR4 Signaling in Hepatocellular Carcinoma
Abstract
Hepatocellular carcinoma (HCC) is the sixth most common type of cancer, with an increasing mortality rate. Aberrant expression of fibroblast growth factor 19–fibroblast growth factor receptor 4 (FGF19–FGFR4) is reported to be an oncogenic-driver pathway for HCC patients. Thus, the FGF19–FGFR4 signaling pathway is a promising target for the treatment of HCC. Several pan-FGFR (1–4) and FGFR4-specific inhibitors are in different phases of clinical...
Paper Details
Title
FGF19–FGFR4 Signaling in Hepatocellular Carcinoma
Published Date
Jun 4, 2019
Journal
Volume
8
Issue
6
Pages
536 - 536
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Notes
History