Aroosha Raja
COMSATS Institute of Information Technology
CancerInternal medicineOncologyReverse transcriptaseVirologyTranscriptomeVirusGrowth factor receptorFGF19CoronavirusHepatocellular carcinomaIGFBP3Nasopharyngeal carcinomaProstate cancerPancreatic cancerSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Real-time polymerase chain reactionFibroblast growth factor receptor 1Cancer researchProportional hazards modelInfectious disease (medical specialty)Clinical trialLoop-mediated isothermal amplificationSignal transductionFibroblast growth factor receptor 4MedicineFibroblast growth factorBiology
3Publications
2H-index
35Citations
Publications 4
Newest
#1Aroosha Raja (CUI: COMSATS Institute of Information Technology)H-Index: 2
#2Farhan Haq (CUI: COMSATS Institute of Information Technology)H-Index: 11
Hepatocellular carcinoma (HCC) is a lethal human malignancy with a very low overall and long-term survival rate. Poor prognostic outcomes are predominantly associated with HCC due to a huge landscape of heterogeneity found in the deadliest disease. However, molecular subtyping of HCC has significantly improved the knowledge of the underlying mechanisms that contribute towards the heterogeneity and progression of the disease. In this review, we have extensively summarized the current information ...
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#1Aroosha Raja (CUI: COMSATS Institute of Information Technology)H-Index: 2
#2Muhammad Faraz Arshad Malik (CUI: COMSATS Institute of Information Technology)H-Index: 8
Last. Farhan Haq (CUI: COMSATS Institute of Information Technology)H-Index: 11
view all 3 authors...
BACKGROUND Fibroblast (FGFs) and insulin (IGF) growth factor pathways are among 10 most recurrently altered genomic pathways in pancreatic ductal adenocarcinoma (PDAC). However, the prognostic and therapeutic relevance of FGF and IGF pathways in PDAC is largely unknown. METHODS We investigated the relationship between fibroblast and insulin pathway gene expression and clinicopathological features in three independent transcriptomic cohorts of 532 PDAC patients. Furthermore, we have examined the ...
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#1Farhan Haq (CUI: COMSATS Institute of Information Technology)H-Index: 11
#2Salmaan SharifH-Index: 19
Last. Muhammad Faraz Arshad Malik (CUI: COMSATS Institute of Information Technology)H-Index: 8
view all 16 authors...
Abstract The sudden outbreak of the novel Coronavirus infectious disease (COVID-19) resulted in significant challenges to global health systems. One of the primary challenges is rapid, reliable, and accurate detection of the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) virus among the suspected COVID-19-infected individuals. At present, quantitative real-time PCR (qRT-PCR) is a widely used diagnostic method. However, it requires expensive instruments and expertise in the interpre...
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#1Aroosha Raja (CUI: COMSATS Institute of Information Technology)H-Index: 2
#2Inkeun Park (Gachon University)H-Index: 22
Last. Sung-Min Ahn (Gachon University)H-Index: 24
view all 4 authors...
Hepatocellular carcinoma (HCC) is the sixth most common type of cancer, with an increasing mortality rate. Aberrant expression of fibroblast growth factor 19–fibroblast growth factor receptor 4 (FGF19–FGFR4) is reported to be an oncogenic-driver pathway for HCC patients. Thus, the FGF19–FGFR4 signaling pathway is a promising target for the treatment of HCC. Several pan-FGFR (1–4) and FGFR4-specific inhibitors are in different phases of clinical trials. In this review, we summarize the informatio...
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