Original paper
Pharmacokinetic and tissue distribution studies of cassane diterpenoids, in rats through an ultra‐high‐performance liquid chromatography–Q exactive hybrid quadrupole–Orbitrap high‐resolution accurate mass spectrometry
Abstract
Cassane diterpenoids (CA) are considered as the main active constituents of medicinal plants belonging to the Caesalpinia genus. Three cassane derivatives, bonducellpin G (BG), 7‐ O ‐acetyl‐bonducellpin C (7‐ O ‐AC) and caesalmin E (CE), isolated from Caesalpinia minax Hance seeds, showed strong anti‐inflammatory activity. In this paper, pharmacokinetics (BG, 7‐ O ‐AC, CE) and tissue distribution (7‐ O ‐AC, CE) properties were studied for the...
Paper Details
Title
Pharmacokinetic and tissue distribution studies of cassane diterpenoids, in rats through an ultra‐high‐performance liquid chromatography–Q exactive hybrid quadrupole–Orbitrap high‐resolution accurate mass spectrometry
Published Date
May 30, 2019
Journal
Volume
33
Issue
10