Evaluation of Nano and Microcapsules of Silymarin in Simulated Gastrointestinal Conditions for Animal Target Delivery

The main goal of this research was to compare the in vitro release rates of nano- and microcapsules of Silybum marianum extract (SME) in animal simulated gastric and intestinal medium conditions. The extract was encapsulated within sodium alginate carriers using emulsification/internal gelation method. Particle size, zeta potential, polydispersity index (PDI) and morphology of nanocapsules were analysed via dynamic light scattering (DLS) and...