Rapid molecular evolution of pain insensitivity in multiple African rodents

Science56.90
Volume: 364, Issue: 6443, Pages: 852 - 859
Published: May 31, 2019
Abstract
Noxious substances, called algogens, cause pain and are used as defensive weapons by plants and stinging insects. We identified four previously unknown instances of algogen-insensitivity by screening eight African rodent species related to the naked mole-rat with the painful substances capsaicin, acid (hydrogen chloride, pH 3.5), and allyl isothiocyanate (AITC). Using RNA sequencing, we traced the emergence of sequence variants in transduction...
Paper Details
Title
Rapid molecular evolution of pain insensitivity in multiple African rodents
Published Date
May 31, 2019
Journal
Volume
364
Issue
6443
Pages
852 - 859
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