Makorin 1 is required for Drosophila oogenesis by regulating insulin/Tor signaling
Abstract
Reproduction is a process that is extremely sensitive to changes in nutritional status. The nutritional control of oogenesis via insulin signaling has been reported; however, the mechanism underlying its sensitivity and tissue specificity has not been elucidated. Here, we determined that Drosophila Makorin RING finger protein 1 gene (Mkrn1) functions in the metabolic regulation of oogenesis. Mkrn1 was endogenously expressed at high levels in...
Paper Details
Title
Makorin 1 is required for Drosophila oogenesis by regulating insulin/Tor signaling
Published Date
Apr 22, 2019
Journal
Volume
14
Issue
4
Pages
e0215688 - e0215688
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