Experiments and Simulations of Complex Sugar-Based Coil−Brush Block Polymer Nanoassemblies in Aqueous Solution

In this work, we investigated the fundamental molecular parameters that guide the supramolecular assembly of glucose-based amphiphilic coil–brush block polymers in aqueous solution and elucidated architecture–morphology relationships through experimental and simulation tools. Well-defined coil–brush polymers were synthesized through ring-opening polymerizations (ROP) of glucose carbonates to afford norbornenyl-functionalized poly(glucose...