Karen L. Wooley
Texas A&M University
MicelleNanoparticleCopolymerMonomerNanotechnologyOrganic chemistryAqueous solutionChemistryNanostructurePolymer chemistryMaterials scienceCombinatorial chemistrySelf-assemblyEthylene glycolAcrylic acidChemical engineeringPolymerizationNanoscopic scalePolymerAmphiphile
434Publications
100H-index
25.1kCitations
Publications 430
Newest
#1Yue Song (A&M: Texas A&M University)H-Index: 6
#2Mahmoud Elsabahy (A&M: Texas A&M University)H-Index: 28
Last. Lu Su (A&M: Texas A&M University)H-Index: 13
view all 14 authors...
Platelet-like and cylindrical nanostructures from sugar-based polymers are designed to mimic the aspect ratio of bacteria and achieve uroepithelial cell binding and internalization, thereby improving their potential for local treatment of recurrent urinary tract infections. Polymer nanostructures, derived from amphiphilic block polymers composed of zwitterionic poly(d-glucose carbonate) and semicrystalline poly(l-lactide) segments, were constructed with morphologies that could be tuned to enhanc...
1 CitationsSource
#1Mahmoud Elsabahy (A&M: Texas A&M University)H-Index: 28
#2Yue Song (A&M: Texas A&M University)H-Index: 6
Last. Karen L. Wooley (A&M: Texas A&M University)H-Index: 100
view all 6 authors...
Abstract Zwitterionic polymer nanoparticles of diverse morphologies (spherical, cylindrical, and platelet-like) constructed from biocompatible sugar-based polymers are designed to extend the pharmacological activities of short- and long-acting insulin peptides, thereby providing potential for therapeutic systems capable of reducing the frequency of administration and improving patient compliance. Amphiphilic block copolymers composed of zwitterionic poly( d -glucose carbonate) and semicrystallin...
1 CitationsSource
#1Mahmoud Elsabahy (Assiut University)H-Index: 28
#2Karen L. Wooley (A&M: Texas A&M University)H-Index: 100
Last. Kenneth J. Oh (Bio-Rad Laboratories)H-Index: 6
view all 4 authors...
Abstract A robust data mining algorithm is presented as a critical solution to the challenge of managing intensive data generated from the recently developed multiplexing techniques, which allow simultaneous detection of up to 500 biomarkers in a few microliters of a single sample. Furthermore, detailed methodology is provided for exploiting the new algorithm along with examples for description of the first application as a powerful diagnostic and therapeutic monitoring tool in the management of...
1 CitationsSource
#1Tan P. Nguyen (A&M: Texas A&M University)H-Index: 3
#2Alexandra D. Easley (A&M: Texas A&M University)H-Index: 7
Last. Karen L. Wooley (A&M: Texas A&M University)H-Index: 100
view all 15 authors...
In only a few decades, lithium-ion batteries have revolutionized technologies, enabling the proliferation of portable devices and electric vehicles1, with substantial benefits for society. However, the rapid growth in technology has highlighted the ethical and environmental challenges of mining lithium, cobalt and other mineral ore resources, and the issues associated with the safe usage and non-hazardous disposal of batteries2. Only a small fraction of lithium-ion batteries are recycled, furthe...
7 CitationsSource
#1Jee Young LeeH-Index: 3
#2Yue SongH-Index: 6
Last. Darrin J. PochanH-Index: 77
view all 4 authors...
#1D. Chase Pectol (A&M: Texas A&M University)H-Index: 2
#2Sarosh Khan (A&M: Texas A&M University)H-Index: 9
Last. Marcetta Y. Darensbourg (A&M: Texas A&M University)H-Index: 65
view all 6 authors...
Rates of NO release from synthetic dinitrosyl iron complexes (DNICs) are shown to be responsive to coordination environments about iron. The effect of biologically relevant cellular components, glutathione and histidine, on the rate of NO release from a dimeric, "Roussin's Red Ester", DNIC with bridging μ-S thioglucose ligands, SGlucRRE or [(μ-SGluc)Fe(NO)2]2 (SGluc = 1-thio-β-d-glucose tetraacetate), was investigated. From the Griess assay and X-band EPR data, decomposition of the product from ...
2 CitationsSource
#1Yue SongH-Index: 6
#2Xin Yang (A&M: Texas A&M University)H-Index: 4
Last. Karen L. WooleyH-Index: 100
view all 7 authors...
The extent of participation of side-chain functionalities during the 1,5,7-triazabicyclo[5.4.0]dec-5-ene (TBD) organobase-catalyzed ring-opening polymerizations (ROP) of six-membered cyclic d-gluco...
5 CitationsSource
#1Jee Young Lee (UD: University of Delaware)H-Index: 3
#2Yue Song (A&M: Texas A&M University)H-Index: 6
Last. Darrin J. Pochan (UD: University of Delaware)H-Index: 77
view all 6 authors...
We report the fibril formation of poly(d-glucose carbonate) (PGC)-based amphiphilic diblock copolymers using solution assembly. Unlike conventional cylindrical micelles constructed from amphiphilic...
3 CitationsSource
#1Yen-Nan Lin (A&M: Texas A&M University)H-Index: 6
#2Sarosh Khan (A&M: Texas A&M University)H-Index: 9
Last. Karen L. Wooley (A&M: Texas A&M University)H-Index: 100
view all 9 authors...
Interactions between drug molecules, nanocarrier components, and surrounding media influence the properties and therapeutic efficacies of nanomedicines. In this study, we investigate the role that ...
5 CitationsSource
#1Mei Dong (A&M: Texas A&M University)H-Index: 7
#2Yue Song (A&M: Texas A&M University)H-Index: 6
Last. Karen L. Wooley (A&M: Texas A&M University)H-Index: 100
view all 11 authors...
In this work, we designed and fabricated a nanoscopic sugar-based magnetic hybrid material that is capable of tackling environmental pollution posed by marine oil spills, while minimizing potential secondary problems that may occur from microplastic contamination. These readily-defined magnetic nanocomposites were constructed through co-assembly of magnetic iron oxide nanoparticles (MIONs) and a degradable amphiphilic polymer, poly(ethylene glycol)-b-dopamine-functionalized poly(ethyl propargyl ...
2 CitationsSource