IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival

Volume: 20, Issue: 5, Pages: 534 - 545
Published: Apr 8, 2019
Abstract
Lymph-node (LN) stromal cell populations expand during the inflammation that accompanies T cell activation. Interleukin-17 (IL-17)-producing helper T cells (TH17 cells) promote inflammation through the induction of cytokines and chemokines in peripheral tissues. We demonstrate a critical requirement for IL-17 in the proliferation of LN and splenic stromal cells, particularly fibroblastic reticular cells (FRCs), during experimental autoimmune...
Paper Details
Title
IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival
Published Date
Apr 8, 2019
Volume
20
Issue
5
Pages
534 - 545
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.