Heme Uptake and Utilization by Gram-Negative Bacterial Pathogens
Abstract
Iron is a transition metal utilized by nearly all forms of life for essential cellular processes, such as DNA synthesis and cellular respiration. During infection by bacterial pathogens, the host utilizes various strategies to sequester iron in a process termed, nutritional immunity. To circumvent these defenses, Gram-negative pathogens have evolved numerous mechanisms to obtain iron from heme. In this review we outline the systems that exist in...
Paper Details
Title
Heme Uptake and Utilization by Gram-Negative Bacterial Pathogens
Published Date
Mar 29, 2019
Volume
9
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