Original paper
Randomized trial comparing standard vs sequential high-dose chemotherapy for inducing early CR in adult AML
Abstract
Here we evaluated whether sequential high-dose chemotherapy (sHD) increased the early complete remission (CR) rate in acute myelogenous leukemia (AML) compared with standard-intensity idarubicin-cytarabine-etoposide (ICE) chemotherapy. This study enrolled 574 patients (age, 16-73 years; median, 52 years) who were randomly assigned to ICE (n = 286 evaluable) or sHD (2 weekly 3-day blocks with cytarabine 2 g/m2 twice a day for 2 days plus...
Paper Details
Title
Randomized trial comparing standard vs sequential high-dose chemotherapy for inducing early CR in adult AML
Published Date
Apr 4, 2019
Journal
Volume
3
Issue
7
Pages
1103 - 1117
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Notes
History