Docetaxel-loaded lipid-polymer hybrid nanoparticles for breast cancer therapeutics

In spite of extensive research over the decades, breast cancer therapy is still a big challenge because of non-specific delivery of the chemotherapy agents and could be overcome by limiting the distribution of chemotherapeutic agents towards the cancer cells. The current study was designed to develop docetaxel (DTX) encapsulated lipid polymer hybrid nanoparticles (LPHNPs-DTX) for controlled and sustained delivery of this drug. LPHNPs-DTX were...