SIRT1 inhibits apoptosis in in�vivo and in�vitro models of spinal cord injury via microRNA-494

Abstract
The aim of the present study was to investigate the function and mechanism of sirtuin 1 (SIRT1) in spinal cord injury (SCI). Reverse transcription‑quantitative polymerase chain reaction was used to measure the expression levels of microRNA (miR)‑494. MTT assay, lactate dehydrogenase activity assay and flow cytometry were used to analyze the effects of miR‑494 on cell growth and apoptosis in a model of SCI. The present study demonstrated that...
Paper Details
Title
SIRT1 inhibits apoptosis in in�vivo and in�vitro models of spinal cord injury via microRNA-494
Published Date
Feb 22, 2019
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